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All's Well for Seroquel

...Now, psychiatrists prescribe Lilly has also combined the two therapies in a single pill called Symbyax.

But Symbyax has not received regulatory approval to treat bipolar mania per se and has a relatively small share of the market.

"Theses guys are like Chevy and Ford or Coke and Pepsi, in terms of their competition, and Seroquel is now more successful than As of Dec.

16, Seroquel held 31.2% of the market share for atypical antipsychotics, one of several classes of drugs used to treat bipolar disorder, according to NDC Health, a pharmaceutical information company, and Friedman Billings Ramsey & Co.

Meanwhile, "Not only is Seroquel now more successful in the marketplace than "It's no longer a 'me-too.'" For most bipolar patients, Seroquel's advantages are clear.

"Generally, the more medications any patient's asked to take, the greater the likelihood that they will miss doses," says Thase....

Study briefs, 1/03: Antipsychotics, kidney disease, foot sores

...About 15 percent of those who took the atypical drugs died within six months of starting them, compared with 18 percent of those using the older-generation drugs.

Overall, the conventional group had a 37 percent greater risk of death than the atypical drug group; risk was highest right after treatment started and for those taking higher doses.

Whether people had dementia or lived in a nursing home did not alter the risk.

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WHO MAY BE AFFECTED BY THESE FINDINGS?

Older people.CAVEATS The FDA concluded that atypical antipsychotics increase the risk of death by 65 percent, compared with taking a placebo.

Based on that, the current study suggests that conventional drugs roughly double a person’s risk of dying, according to the authors.

The study did not reveal causes of death, nor did it determine how or why antipsychotics affect mortality risk.FIND THIS STUDY Dec.

1 issue of the New England Journal of Medicine; abstract available online at www.nejm.org.LEARN MORE ABOUT antipsychotics at www.intelihealth.com (search for “antipsychotic drugs” in quotation marks) and www.nimh.nih.gov.A transplant rejection drug may help stem kidney diseaseTHE QUESTION For three decades, the standard treatment for people with inflamed kidneys brought on by lupus, known as lupus nephritis, has been a chemotherapy drug.

Side effects, however, can be severe, including infertility.

Might a newer drug &md...

Attorney: off his medication, man stabs two neighbors

... Dr.

Frederick Kelso said Westbrook has been hospitalized for his illness in the past and was quiet, distant, depressed and sad Thursday.

"He plainly told me at one point, ’I don’t know why I’m here’" Kelso told Assistant District Attorney Jacqueline Shanahan.

Westbrook, 20, of 25 Cheney St., was charged with home invasion and two counts of armed assault with intent to murder when he was arrested about 2:30 a.m.

yesterday, District Attorney spokeswoman Kathryn Norton said.

He was arrested when an officer found him walking near the intersection of Mechanic and Cheney streets, hours after the 8 p.m.

attack.

He was hostile, uncooperative and swore at police during booking, according to a police report.

He also refused to be fingerprinted.

Westbrook was ordered by Newton District Court Judge Margaret Zaleski, on the advice of his attorney, Arthur Kelly, and Kelso, to undergo a psychiatric evaluation at Bridgewater State Hospital.

"I have concerns about (Westbrook’s) ability to stand trial," Kelso said.

Westbrook pleaded not guilty, but did not appear in the courtroom during his arraignment yesterday.

He stood out of sight of news cameras as he spoke to Zaleski.

He is expected back in Newton District Court Jan.

17.

Westbrook is accused of walking through Claudia and Jin Chung’s unlocked kitchen door at 21 Cheney St.

with a knife about 7:50 p.m.

Thur...

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